Crystalline forms and two solvated forms of...

Details Crystalline forms and two solvated forms of... Crystalline forms and two solvated forms of...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2718076

Crystalline forms or polymorphs of 4-amino -5-fluoro-3-[5-(4-methylpiperazin-1- yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one lactic acid salts, as well as to methods of making the same, pharmaceutical compositions comprising the same and methods of treatment using the same.

Linvention concerne des formes cristallines ou des polymorphes de lactates de 4-amino-5-fluoro-3-[5-(4-méthylpipérazin-1-yl)-1H-benzimidazol-2-yl] quinolin-2(1H)-one, ainsi que leurs procédés de préparation, des compositions pharmaceutiques les comprenant et des procédés de traitement les utilisant.

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