Crystalline forms of valacyclovir hydrochloride

C - Chemistry – Metallurgy – 07 – D

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C07D 473/18 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2457835

Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and phamaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate.

La présente invention concerne de nouveaux polymorphes et pseudopolymorphes du chlorhydrate de valacyclovir et des compositions pharmaceutiques les contenant. L'invention se rapporte également à des procédés de fabrication de ces nouveaux polymorphes et pseudopolymorphes, parmi lesquels le chlorhydrate de valacyclovir monohydrate et le chlorhydrate de valacyclovir dihydrate.

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