C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2644649
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, t, R1 , R2 , R3, R4, R5, R6, R7, Q, Y and Z have defined meanings.
La présente invention concerne des composés répondant à la formule (I), leur utilisation en tant qu'inhibiteurs d'une interaction entre les gènes p53 et MDM2, aussi bien que des compositions pharmaceutiques contenant lesdits composés répondant à la formule (I), n, m, p, t, R1 , R2 , R3, R4, R5, R6, R7, Q, Y et Z ayant les significations définies.
Contreras Jean-Marie
Giethlen Bruno
Joubert Muriel
Lacrampe Jean Fernand Armand
Meyer Christophe
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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