Cyclization to form cephem ring and intermediates therefor

Details Cyclization to form cephem ring and intermediates therefor Cyclization to form cephem ring and intermediates therefor

C - Chemistry, Metallurgy

07

D

260/245.1, 260/3

C07D 205/08 (2006.01) C07D 205/095 (2006.01) C07D 513/04 (2006.01)

Patent

CA 1077936

ABSTRACT OF THE DISCLOSURE An intermediate represented by the following formula for synthesizing 3-hydroxy-3-cephem compounds. Image wherein R' is the terminal group of carboxylic acid acyl radical; R3 is hydrogen, isopropenyl, isopropylidene, 1-hydroxyethylidene, Image X is hydroxy or carboxy-protecting group; Y is disubstituted amino and Hal is halogen.

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