C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/06 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/33 (2006.01) C07C 233/60 (2006.01) C07C 233/63 (2006.01) C07C 235/40 (2006.01) C07C 235/82 (2006.01) C07C 237/24 (2006.01) C07D 295/185 (2006.01) C07D 317/40 (2006.01)
Patent
CA 2072126
2072126 9110644 PCTABS00006 Compounds of formula (I), wherein A completes a 4 to 7 membered carbocyclic ring which may be saturated or mono-unsaturated and which may optionally be fused to a further saturated or unsaturated 5 or 6 membered carbocyclic ring; R is H, C1-C6 alkyl, benzyl or an alternative biolabile ester-forming group; R1 is H or C1-C4 alkyl; R2 is H, OH, C1-C4 alkyl, C1-C4 alkoxy, halo or CF3; R3 is CH2OH or CO2R4 where R4 is as defined for R; and R5 is defined to include a range of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, and substituted alkyl groups including in particular methoxyethyl, S-lysylamino-methyl, N2-acetyl-S-lysylaminomethyl and N2-methanesulphonyl-S-lysyl-aminomethyl, are atriopeptidase inhibitors of utility in the treatment of hypertension, heart failure, renal insufficiency and other disorders
Barnish Ian T.
Brown David
Danilewicz John C.
James Keith
Barnish Ian T.
Brown David
Danilewicz John C.
James Keith
Limited Pfizer
LandOfFree
Cycloalkyl-substituted glutaramide diuretic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cycloalkyl-substituted glutaramide diuretic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cycloalkyl-substituted glutaramide diuretic agents will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1695978