Cyclohexyl sulphones as gamma-secretase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 317/30 (2006.01) A61K 31/10 (2006.01) A61P 25/28 (2006.01) C07D 207/04 (2006.01) C07D 213/70 (2006.01) C07D 213/71 (2006.01) C07D 213/74 (2006.01) C07D 231/18 (2006.01) C07D 233/42 (2006.01) C07D 249/12 (2006.01) C07D 257/04 (2006.01) C07D 261/10 (2006.01) C07D 275/03 (2006.01) C07D 277/36 (2006.01) C07D 295/088 (2006.01) C07D 295/10 (2006.01) C07D 307/64 (2006.01) C07D 333/34 (2006.01)

Patent

CA 2500969

Compounds of formula (I) inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.

L'invention concerne des composés de formule (I). Ces composés inhibent la transformation de la protéine précurseur amyloïde (APP) par gamma-sécrétase. Ces composés sont donc utiles dans le traitement et la prévention de la maladie d'Alzheimer.

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