Cyclohexylamino, benzene, pyridine, and pyridazine derivatives

Details Cyclohexylamino, benzene, pyridine, and pyridazine derivatives Cyclohexylamino, benzene, pyridine, and pyridazine derivatives

C - Chemistry, Metallurgy

07

D

C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) C07D 231/56 (2006.01)

Patent

CA 2642931

Disclosed are compounds and pharmaceutically acceptable salts of Formula (I), wherein Q1, Q2, RN, R1, R2, R5, R6, R7, Rs, X1, X2, X4, and Y are as defined herein. Compounds of Formula (I) are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds .

L'invention concerne des composés et des sels pharmaceutiquement acceptables de formule (I), dans laquelle Q1, Q2, RN, R1, R2, R5, R6, R7, Rs, X1, X2, X4 et Y sont tels que définis dans le présent document. Les composés de formule (I) sont utiles pour le traitement de maladies et/ou de troubles liés à la prolifération cellulaire, tels que le cancer, l'inflammation, l'arthrite, l'angiogenèse ou similaires. L'invention concerne également des compositions pharmaceutiques comprenant des composés selon l'invention et des procédés de traitement des états susmentionnés en utilisant de tels composés.

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