Cysteine protease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/04 (2006.01) A61K 31/422 (2006.01) A61K 31/423 (2006.01) A61K 31/424 (2006.01) A61K 31/4245 (2006.01) C07D 263/56 (2006.01) C07D 271/06 (2006.01) C07D 271/10 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2484011

The present invention is directed to compounds that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

L'invention concerne des composés qui inhibent la cystéine protéase, en particulier les cathepsines B, K, L, F, et S, et qui servent par conséquent à traiter les maladies induites par ces protéases. Par ailleurs, l'invention concerne des compositions pharmaceutiques qui renferment ces composés ainsi que des procédés de préparation correspondants.

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