Cytoprotective fatty moiety compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 69/58 (2006.01) C07C 69/50 (2006.01) C07C 69/60 (2006.01) C07C 69/732 (2006.01) C07C 211/08 (2006.01) C07C 219/08 (2006.01) C07C 233/09 (2006.01) C07C 233/20 (2006.01) C07C 233/38 (2006.01) C07C 233/49 (2006.01) C07C 235/76 (2006.01) C07C 309/14 (2006.01) C07D 207/16 (2006.01) C07D 265/32 (2006.01) C07D 307/24 (2006.01) C07D 333/38 (2006.01) C11C 3/00 (2006.01)

Patent

CA 2064783

Water or lipid soluble, pharmacologically active, antioxidant, anti- phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at least two fatty moieties and no active hydroxy group. The compound may also have at least one ionizable group, which may a carboxyl group, and each of the fatty moieties has from sixteen to twenty carbon atoms and at least one cis-unsaturated double bond.

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