Cytotoxic n, n'-bis (succinyl-peptide)-derivatives of...

Details Cytotoxic n, n'-bis (succinyl-peptide)-derivatives of... Cytotoxic n, n'-bis (succinyl-peptide)-derivatives of...

C - Chemistry, Metallurgy

07

K

C07K 5/04 (2006.01) A61K 38/04 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07C 237/22 (2006.01) C07C 279/14 (2006.01) C07D 207/416 (2006.01) C07D 207/46 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/09 (2006.01) C07K 5/093 (2006.01) C07K 5/103 (2006.01) C07K 5/113 (2006.01) C07K 7/06 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2036007

30,723-00 TITLE OF THE INVENTION CYTOTOXIC N,N'-BIS(SUCCINYL-PEPTIDE)-DERIVATIVES OF 1,4-BIS(AMINOALKYL)-5,8-DIHYDROXYANTHROQUINONES AND ANTIBODY CONJUGATES THEREOF ABSTRACT OF THE DISCLOSURE The present invention is concerned with novel N,N'-bis(succinyl-peptide)-derivatives of 1,4-bis- (aminoalkyl)-5,8-dihydroxyanthraquinones and the corresponding antibody conjugates thereof each of which have potential use in the treatment of human carcinomas.

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