C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2472479
The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
L'invention concerne des composés de formule (I), dans laquelle R¿1?, R¿2?, R¿3? et n sont tels que décrits de façon générale et définis en classes et sous-classes dans la description. L'invention se rapporte en outre à des compositions pharmaceutiques de ces composés ainsi qu'à des procédés d'utilisation de ces composés pour traiter des troubles inflammatoires ou auto-immuns et prolifératifs, et en tant qu'inhibiteurs de l'expression des molécules d'adhésion cellulaire et de la transduction des signaux des cytokines inflammatoires d'une manière générale.
Daun Jane
Davis Heather A.
de Costa Bruce
Gusovsky Fabian
Hishinuma Ieharu
Eisai Co. Ltd.
Eisai R&d Management Co. Ltd.
Robic
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