Decolorizing contrast media intermediates

Details Decolorizing contrast media intermediates Decolorizing contrast media intermediates

C - Chemistry, Metallurgy

07

C

C07C 231/24 (2006.01) C07C 237/46 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2710582

This invention relates generally to synthesis of non-ionic X-ray contrast agents. It further relates to an improved method for the synthesis of 5-amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (Compound B), an intermediate in the industrial preparation of non-ionic X-ray contrast agents. In particular, it relates to a process for decolorizing said intermediate.

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