C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 39/04 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2477195
The present invention is the identification of a nucleotide sequence which make it possible in particular to distinguish an infection resulting from the vast majority of Mycobacterium tuberculosis strains from an infection resulting from Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, Mycobacterium bovis, Mycobacterium bovis BCG. The subject of the present invention is also a method for detecting the sequences in question by the products of expression of these sequences and the kits for carrying out these methods. Finally, the subject of the present invention is novel vaccines.
La présente invention concerne l'identification d'une séquence nucléotidique qui rend possible en particulier la distinction entre une infection résultant d'une large majorité de souches de <i>Mycobacterium tuberculosis</i> d'une infection résultant de <i>Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, Mycobacterium bovis, Mycobacterium bovis BCG</i>. L'invention a également pour objet un procédé de détection des séquences mentionnées grâce aux produits d'expression de ces séquences et des kits pour mettre en oeuvre ces procédés. Pour finir, l'invention concerne de nouveaux vaccins.
Brosch Roland
Cole Stewart
Eiglmeier Karin
Garnier Thierry
Gordon Stephen
Institut Pasteur
Robic
Veterinary Laboratories Agency
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