C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/00 (2006.01) A61K 31/715 (2006.01) A61K 51/00 (2006.01) A61K 51/06 (2006.01)
Patent
CA 2185663
A preparation of a delipidated purified polysaccharide compound D25 with a molecular weight of around 34 KD, extracted from the membrane proteoglycans of Klebsiella pneumoniae, wherein said polysaccharide compound is delipidated and purified so that an aqueous solution containing the compound no longer comprises any C¿16? fatty acids and peptides whether free or combined with said compound. The use of said preparation in imaging, given the targeting properties of said compound, is also disclosed.
La présente invention décrit une préparation d'un composé polysaccharidique D25 délipidé et purifié, de poids moléculaire d'environ 34 KD, pouvant être obtenu par extraction à partir des protéoglycanes membranaires de Klebsiella pneumoniae, caractérisée en ce que ledit composé polysaccharidique est délipidé et purifié de sorte que ladite solution aqueuse ne comporte pas de formes micellaires dudit composé. Ladite préparation ne comporte plus d'acides gras au C-16 et de peptides sous forme libre ou associée audit composé. La présente invention concerne également l'utilisation de cette préparation en imagerie compte tenu des propriétés de ciblage dudit composé.
Binz Hans
Cudennec Claude-Alain
Durand Jacques
Le Pape Alain
Normier Gerard
Pierre Fabre Medicament
Swabey Ogilvy Renault
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