C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 35/74 (2006.01) A61K 36/06 (2006.01) A61K 36/064 (2006.01) A61P 1/00 (2006.01) C12N 1/16 (2006.01) C12N 15/74 (2006.01) C12N 15/81 (2006.01)
Patent
CA 2672229
The present invention relates to the delivery of binding molecules, such as antibodies, antibody fragments, single antibody variable domains, soluble receptors, ligands and dominant negative variants, to induce an immunomodulation in a patient. More specifically, the invention relates to the production of a medicament comprising said binding molecules producing micro-organisms, and the use of this medicament in the treatment of immune mediated diseases.
La présente invention concerne la délivrance de molécules de liaison, telles que des anticorps, des fragments d'anticorps, des domaines variables d'anticorps simples, des récepteurs solubles, des ligands et des variants dominants négatifs, pour induire une immunomodulation chez un patient. De manière plus spécifique, l'invention concerne la production d'un médicament comprenant des micro-organismes produisant lesdites molécules de liaison, et l'utilisation de ce médicament dans le traitement de maladies à médiation immunitaire.
de Creus An
Rottiers Pieter
Actogenix N.v.
Smart & Biggar
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