Dentin chondrogenic inductive agent

C - Chemistry – Metallurgy – 07 – K

Patent

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530/15.06

C07K 14/78 (2006.01)

Patent

CA 2001978

ABSTRACT A cartilage-inducing factor has been isolated from dentin and characterized as a polypeptide having an apparent molecular weight of 6,000 to 8,500, an isoelectric pH of from 4.5 to 6.5, and, biologically, as being capable of inducing muscle fibroblast cells to produce cartilage-specific proteo- glycan and Type II collagen.

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