C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/266.3, 260/2
C07D 471/04 (2006.01) C07D 209/88 (2006.01)
Patent
CA 1138459
ABSTRACT OF THE DISCLOSURE The novel derivatives correspond to the general formula: Image (I) in which R1 is a Y-(CH2)n -NR4R5 group, where Y represents a single bond or the group Image , R4 and R5, identical or different, are hydrogen or an alkyl radical, preferably a lower alkyl, or again form together a ring which can include heteroatoms, in particular nitrogen atoms. n is a number ranging from 1 to 10, notably from 2 to 7, R2 is a hydrogen atom, a lower alkyl group or an aralkyl group in which the alkyl sub- stituent is a lower alkyl group, and R3 is a hydrogen atom or a CH3 group. The compounds have antitumoral and antiviral properties useful for the treatment of cancers.
336000
Bisagni Emile
Chermann Jean-Claude
Civier Alain
Ducrocq Claire
Gruest Jacqueline
Agence Nationale de Valorisation de La Recherche (anvar)
Gowling Lafleur Henderson Llp
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