C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2267155
A method and kit for predicting increased risk of sight-threatening diabetic retinopathy which includes isolating genomic DNA from a sample from a diabetic patient. The genetic polymorphism pattern for the genes IL-1A, IL-1B and IL-1RN is then identified in the DNA. The identified pattern is compared with control patterns of known polymorphisms and patients expressing a genetic polymorphism pattern associated with increased risk of sight-threatening diabetic retinopathy are identified.
Méthode et trousse permettant de prédire un risque accru de rétinopathie diabétique avec risque d'atteinte de la vision, qui comportent l'isolement de l'ADN génomique à partir d'un échantillon prélevé chez un patient diabétique. Le motif de polymorphisme génétique pour les gènes IL-1A, IL-1B et IL-1RN est ensuite identifié dans l'ADN. Le motif identifié est comparé à des motifs témoins de polymorphismes connus, ce qui permet d'identifier les patients exprimant un motif associé à un risque accru de rétinopathie diabétique avec risque d'atteinte de la vision.
Duff Gordon
Rennie Ian
Richardson Robert
Borden Ladner Gervais Llp
Duff Gordon
Interleukin Genetics Inc.
Rennie Ian
Richardson Robert
LandOfFree
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