Detecting triazole resistance in aspergillus

Details Detecting triazole resistance in aspergillus Detecting triazole resistance in aspergillus

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2686337

Methods are provided for detecting triazole -resistant fungi in a sample. The methods comprise evaluating the sample for the presence of a gene encoding a mutant AzRFl transcription factor, or the level of the transcription factor, to determine whether a fungus is triazole-resistant. Primers, probes and kits also are provided.

L'invention propose des procédés pour détecter des champignons résistant au triazole dans un échantillon. Les procédés comportent l'évaluation de l'échantillon pour déterminer la présence d'un gène codant pour un facteur de transcription AzRFl mutant, ou le niveau du facteur de transcription, pour déterminer si un champignon est résistant au triazole ou non. Des amorces, des sondes et des kits sont également fournis.

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