Detection of nucleic acids by type-specific hybrid capture...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2413020

Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA/RNA hybrids which can be detected by a variety of methods.

L'invention concerne la capture hybride de cible spécifique (TSHC) offrant un procédé de détection d'acide nucléique qui n'est pas seulement rapide et sensible mais aussi très spécifique et capable de distinguer des séquences de cible d'acide nucléique hautement homologues. Ce procédé produit des hybrides ADN/ARN pouvant être détectés par divers procédés.

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