Deuterated benzylbenzene derivatives and methods of use

Details Deuterated benzylbenzene derivatives and methods of use Deuterated benzylbenzene derivatives and methods of use

A - Human Necessities

61

K

A61K 31/351 (2006.01) A61K 31/047 (2006.01) A61K 31/085 (2006.01) A61K 31/122 (2006.01) A61P 3/00 (2006.01) A61P 9/10 (2006.01) C07B 59/00 (2006.01) C07C 29/00 (2006.01) C07C 41/01 (2006.01) C07C 45/00 (2006.01) C07D 309/10 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2730734

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

La présente invention concerne des composés ayant un effet inhibiteur sur le cotransporteur de glucose sodium-dépendant SGLT. Linvention concerne en outre des compositions pharmaceutiques, des procédés de préparation des composés, des intermédiaires de synthèse et des procédés dutilisation des composés, indépendamment ou en combinaison avec dautres agents thérapeutiques, pour traiter des maladies et des pathologies qui sont affectées par linhibition de SGLT.

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