Device and method for mixing magnetic particles with a fluid

Details Device and method for mixing magnetic particles with a fluid Device and method for mixing magnetic particles with a fluid

B - Operations, Transporting

01

F

B01F 13/08 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2379773

This invention relates to the use of magnetic or magnetizable particles, and, in particular, to methods of mixing magnetic or (super)paramagnetic particles efficiently with a fluid and the separation of the magnetic particles from a fluid, optionally followed by resuspension of the particles in another fluid. The present invention provides a method of mixing, in one or more container(s), magnetic or (super)paramagnetic particles with a fluid, using more than one magnets, whereby the containers are subjected to magnetic fields with different and changing directions by moving the magnets with respect to the position of the container(s) and/or by moving the containers with respect to the positions of the magnets. The invention further provided a device for doing the same. Preferably the holders for the containers and the magnets in the device are placed in intervening array geometries and the magnets are placed in line in such a way that all magnets that are in line have their poles oriented in the same direction, and that all magnets in a neighboring line have their poles oriented in the reverse direction with respect to the poles of the magnets in the first line.

Cette invention concerne l'utilisation de particules magnétiques ou magnétisables et, notamment, des procédés qui permettent de mélanger efficacement des particules magnétiques ou (super)paramagnétiques à un fluide, de séparer les particules magnétiques du fluide et, éventuellement, de remettre les particules en suspension dans un autre fluide. Cette invention offre un procédé qui permet de mélanger, dans un ou plusieurs conteneurs, des particules magnétiques ou (super)paramagnétiques à un fluide, ceci à l'aide d'un ou de plusieurs aimants. Les conteneurs sont soumis à des champs magnétiques qui ont des directions différentes et variables, ceci grâce au déplacement des aimants par rapport à la position du conteneur et/ou grâce au déplacement des conteneurs par rapport à la position des aimants. Cette invention concerne également un dispositif permettant de mettre en oeuvre ce procédé. Les supports des conteneurs et des aimants du dispositifs sont de préférence disposés selon des géométries de réseaux intercalés. Les aimants sont quant à eux disposés en ligne de sorte que tous les aimants alignés aient leurs pôles orientés dans une même direction et de sorte que les aimants d'une ligne voisine aient leurs pôles orientés dans la direction opposée à celle des pôles des aimants de la première ligne.

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