Devices and methods for detection of an analyte based upon...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C12M 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 21/21 (2006.01) G01N 21/27 (2006.01) G01N 21/45 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2141324

Methods for analyzing an optical surface for an analyte of interest in a test sample and related instruments/devices are dis- closed. The method entails the use of thin film optical immunoassay device whereby an analyte of interest is detected in a test sample through spectral changes in the light impinging the surface prior to and after the binding of the analyte to reactive sub- strate layer(s). The device includes a substrate which has a first color in response to light impinging thereon. The substrate also exhibits a second color which is different from the first color. The second color is exhibited in response to the same light when the analyte is present on the surface.

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