Devices and methods for enrichment and alteration of cells...

C - Chemistry – Metallurgy – 12 – M

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12M 1/34 (2006.01) C12M 3/00 (2006.01) C12N 5/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2601480

The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.

L'invention porte sur des dispositifs et des procédés de séparation déterministique de particules. Certains des procédés donnés en exemple consistent à enrichir un échantillon en particules désirées ou à modifier certaines particules. Les dispositifs et les procédés s'utilisent notamment pour l'enrichissement en cellules rares, par exemple les cellules foetales, présentes par exemple dans le sang maternel, ou en composants de cellules rares, par exemple des noyaux de cellules foetales. L'invention porte également sur un procédé de lyse préférentielle de cellules d'intérêt d'un échantillon, par exemple pour extraire des informations cliniques d'un composant de cellules d'intérêt, par exemple le noyau. En général, la méthode utilise à cet effet une lyse différentielle entre les cellules d'intérêt et les autres (par exemple les autres cellules nucléées) de l'échantillon.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Devices and methods for enrichment and alteration of cells... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Devices and methods for enrichment and alteration of cells..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Devices and methods for enrichment and alteration of cells... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1747103

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.