C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) C07G 99/00 (2009.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/68 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2269646
Provided are protective and deleterious diabetes-mediating proteins and polynucleotides encoding same, transgenic animals expressing a diabetes- mediating protein, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of altering the expression of a diabetes-mediating protein.
L'invention concerne des protéines médiatrices du diabète, protectrices et néfastes, les polynucléotides codant pour lesdites protéines, des animaux transgéniques exprimant une protéine médiatrice du diabète, des méthodes de criblage de médicaments qui permettent d'identifier un composé test capable de modifier l'expression desdites protéines, ainsi que des méthodes qui permettent de prévenir ou d'améliorer le diabète en administrant un composé capable de modifier l'expression d'une protéine médiatrice du diabète.
Andersen Henrik U.
Bjerre Christensen Ulla
Fey Stephen J.
Karlsen Allan E.
Larsen Peter Mose
Andersen Henrik U.
Bjerre Christensen Ulla
Fey Stephen J.
Gowling Lafleur Henderson Llp
Karlsen Allan E.
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