C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/088 (2006.01) A61K 31/495 (2006.01) A61P 33/06 (2006.01) A61P 43/00 (2006.01) C07D 295/084 (2006.01)
Patent
CA 2429539
Dibenzosuberanyl piperazine derivatives represented by the following general formula (I) wherein R represents optionally substituted aliphatic hydrocarbyl containing a hetero atom and preferably having 2 to 30 carbon atoms; physiologically acceptable salts thereof, and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof. These compounds have an effect of restoring the sensitivity to a drug of a factor causative of a disease which has acquired the resistance against the drug, i.e., an effect of overcoming the resistance.
L'invention concerne des dérivés de pipérazine dibenzosubéranyle représentés par la formule générale suivante (I), dans laquelle R représente un hydrocarbyle aliphatique éventuellement substitué contenant un atome hétéro et contenant, de préférence, entre 2 et 30 atomes de carbone, leurs sels acceptables sur le plan physiologique, et des compositions médicinales contenant ces dérivés de pipérazine dibenzosubéranyle et/ou leurs sels acceptables sur le plan physiologique. Ces composés permettent de restaurer la sensibilité à un médicament d'un facteur causal d'une maladie qui a acquit la résistance au médicament, par exemple, en surmontant cette résistance.
Kobayashi Seiki
Miyata Yoshiyuki
Osa Yumiko
Sakaguchi Masakazu
Sato Yoko
Gowling Lafleur Henderson Llp
Pola Chemical Industries Inc. Japan
Takayanagi Hiroaki
Takeuchi Tsutomu
LandOfFree
Dibenzosberanyl piperazine derivatives and drug-resistance... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dibenzosberanyl piperazine derivatives and drug-resistance..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dibenzosberanyl piperazine derivatives and drug-resistance... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1722401