Dicarboxamide derivatives and their use as factor xa inhibitors

Details Dicarboxamide derivatives and their use as factor xa inhibitors Dicarboxamide derivatives and their use as factor xa inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61P 7/02 (2006.01) C07D 213/75 (2006.01) C07D 233/54 (2006.01) C07D 279/02 (2006.01) C07D 295/12 (2006.01) C07D 295/18 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2585615

The invention is concerned with novel dicarboxamide derivatives of formula (I) wherein A, B, RC, D and E are as defined in the description and in the claims, as well 5as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.

L'invention porte sur de nouveaux dérivés de dicarboxamide représentés par la formule (I) dans laquelle A, B, RC, D et E sont tels que définis dans le descriptif et dans les revendications, ainsi que sur des sels physiologiquement acceptables de ceux-ci. Ces composés inhibent le facteur Xa de coagulation et peuvent être utilisés comme médicaments.

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