Dihydrobenzo[b]indeno[2,1-d]thiophene compounds,...

Details Dihydrobenzo[b]indeno[2,1-d]thiophene compounds,... Dihydrobenzo[b]indeno[2,1-d]thiophene compounds,...

C - Chemistry, Metallurgy

07

D

C07D 333/78 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2214176

The invention provides dihydrobenzo[b]indenothiophene compounds, intermediates, processes, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, cardiovascular-related pathological conditions including hyperlipidemia and related cardiovascular pathologies, and estrogen-dependent cancer.

L'invention porte sur des composés de dihydrobenzo[b]indénothiophène, des intermédiaires, des procédés, des formulations et des méthodes pour inhiber la perte osseuse ou la résorption osseuse, particulièrement l'ostéoporose, et les états pathologiques apparentés aux maladies cardio-vasculaires, dont l'hyperlipidémie, et d'autres affections cardio-vasculaires, et le cancer oestrogéno-dépendant.

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