C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A01K 67/027 (2006.01) A23C 9/127 (2006.01) A23C 9/20 (2006.01) A61K 38/46 (2006.01) C07H 21/04 (2006.01) C12N 5/10 (2006.01) C12N 9/20 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2137815
The present invention relates to a DNA molecule containing intron sequences and encoding a human protein which is, de-pending on the site of action, called Bile Salt-Stimulated Lipase (BSSL) or Carboxyl Ester Lipase (CEL). The DNA molecule is advantageously used in the production of recombinant human BSSL/CEL, preferably by means of production in transgenic non--human mammals. The recombinant human BSSL/CEL can be used as a constituent of infant formulas used for feeding infants as a substitute for human milk, or in the manufacture of medicaments against e.g. fat malabsorption, cystic fibrosis and chronic pancreatitis.
Bjursell Karl Gunnar
Carlsson Peter Nils Ivar
Enerback Curt Sven Magnus
Hansson Stig Lennart
Lidberg Ulf Fredrik Pontus
Aktiebolaget Astra
Arexis Ab
Fetherstonhaugh & Co.
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