Dpp-iv inhibitor including beta-amino group, preparation...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 241/08 (2006.01) A61K 31/4704 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2683696

The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.

L'invention porte sur un nouveau composé hétérocyclique contenant un groupe bêta-amino, sur sa méthode de préparation et sur une composition pharmaceutique le comprenant ou l'un de ses sels pharmaceutiquement acceptable comme principe actif. Ledit composé présente une excellente activité inhibitrice du DPP-IV et une excellente biodisponibilité et s'avère donc utile pour la prophylaxie ou le traitement de maladies liées au DPP-IV telles que le diabète ou l'obésité.

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