Dpp-iv inhibitors

Details Dpp-iv inhibitors Dpp-iv inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/40 (2006.01) A61K 31/343 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/4409 (2006.01) A61K 31/505 (2006.01) C07C 237/20 (2006.01) C07C 311/13 (2006.01) C07D 231/12 (2006.01) C07D 241/12 (2006.01) C07D 261/08 (2006.01) C07D 295/13 (2006.01) C07D 307/79 (2006.01) C07D 311/76 (2006.01) C07D 319/16 (2006.01)

Patent

CA 2558446

The invention relates to compounds of formula (I), Z-C(R1R2)-C(R3NH2)-C(R4R5)- X-N(R6R7), wherein Z, R1-7 and X have the meaning as cited in the description and the claims. Said compounds are useful as DPP-lV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.

L'invention concerne des composés représentés par la formule (I) suivante: Z-C(R?1¿R?2¿)-C(R?3¿NH¿2?)-C(R?4¿R?5¿)-X-N(R?6¿R?7¿). Dans cette formule Z, R?1-7¿ et X sont tels que définis dans la description et les revendications. Ces composés sont utiles en tant qu'inhibiteurs de dipeptidyl peptidase IV. L'invention concerne également la préparation de ces composés, ainsi que la production et l'utilisation de ceux-ci en tant que médicament.

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