Drug metabolizing enzymes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/52 (2006.01) A01K 67/027 (2006.01) A61K 38/43 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/04 (2006.01) C12N 9/10 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2403644

The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.

L'invention concerne des enzymes métabolisant les médicaments (DME) et des polynucléotides codant pour ces enzymes DME et les identifiant. Elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention se rapporte en outre à des procédés de diagnostic, de traitement ou de prévention de troubles associés à l'expression aberrante de ces enzymes DME.

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