Drug microparticles

Details Drug microparticles Drug microparticles

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61K 31/59 (2006.01) A61K 31/7048 (2006.01)

Patent

CA 2647073

Pharmaceutical compositions are described containing carrier particles bearing microparticles of a drug. The drug microparticles may be deposited on the carrier particles, for example, by sublimation. Preferred embodiments of these pharmaceutical compositions are suitable for administration by inhalation or injection. Methods for treating lung infection in patients with cystic fibrosis through inhalation of, for example, calcitriol compositions, are also described.

L'invention concerne des compositions pharmaceutiques contenant des particules de support servant de support à des microparticules d'un médicament. Les microparticules médicamenteuses peuvent être déposées sur les particules de support, par exemple, par sublimation. Des modes de réalisation préférés de ces compositions pharmaceutiques permettent une administration par inhalation ou injection. L'invention concerne également des méthodes destinées à traiter une infection pulmonaire chez des patients atteints de mucoviscidose par inhalation de compositions de calcitriol, par exemple.

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