Dtpa derivatives substituted in a novel way, their metal...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 5/00 (2006.01) A61K 31/195 (2006.01) A61K 31/28 (2006.01) A61K 31/395 (2006.01) A61K 31/555 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/06 (2006.01) A61K 51/00 (2006.01) C07C 229/36 (2006.01) C07C 237/20 (2006.01) C07C 323/58 (2006.01) C07D 295/185 (2006.01) C07F 19/00 (2006.01)

Patent

CA 2206576

The invention concerns novel diethylenetriamine pentaacetic acid (DTPA) derivatives, their complexes and complex salts, containing an element of the atomic numbers 20 - 32, 39 - 51 or 57 - 83. The invention further concerns pharmaceutical compositions containing these compounds, their preparation and their use as contrast media and antidotes.

L'invention concerne de nouveaux dérivés d'acide pentacétique de diéthylène triamine (DTPA), leurs complexes et leurs sels complexes, contenant un élément ayant comme nombre atomique 20-32, 39-51 ou 57-83. L'invention concerne en outre des formulations pharmaceutiques contenant ces composés, leur préparation et leur utilisation comme agents de contraste et comme antidote.

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