Dual-action inhibitors and methods of using same

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/56 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61K 31/416 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61K 31/55 (2006.01) C07C 237/30 (2006.01) C07C 237/42 (2006.01) C07D 217/02 (2006.01) C07D 237/28 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2760611

Provided are compounds, compositions, and methods for treating diseases and conditions wherein an inhibitor of a kinase, such as rho kinase (ROCK), and an inhibitor of one or more of the monoamine transporters, such as NET or SERT, act in concert to improve the condition.

L'invention concerne des composés, des compositions et des méthodes pour traiter des maladies et des troubles, dans lesquels un inhibiteur de la kinase, tel que la rho kinase (ROCK), et un inhibiteur d'un ou de plusieurs transporteurs de monoamines, tels que NET ou SERT, agissent conjointement pour améliorer le trouble.

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