E.coli heat-labile enterotoxin subunit b (etxb) as an...

A - Human Necessities – 61 – K

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Details

A61K 39/12 (2006.01) A61K 38/16 (2006.01) A61K 39/245 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2331832

There is disclosed the use of: (i) EtxB, CtxB or VtxB free from whole toxin; (ii) an agent other than EtxB or CtxB, having GM1-binding activity, or an agent other than VtxB having Gb3-binding activity; or (iii) an agent having an effect on intracellular signalling events mediated by GM1-binding or Gb3 binding; as an immunomodulator for a vaccine against infectious diseases.

L'invention concerne l'utilisation (i) de EtxB, CtxB ou de VtxB exempt de toute toxine, (ii) d'un agent autre que EtxB ou CtxB ayant une activité de liaison GM1, ou d'un agent autre que VtxB ayant une activité de liaison Gb3, ou (iii) d'un agent ayant un effet sur des événements de transmission de signaux intracellulaires dont la médiation est assurée par liaison GM1 ou Gb3, comme immunomodulateur pour un vaccin contre des maladies infectieuses.

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