East coast fever vaccine based on ctl-specific schizont...

Details East coast fever vaccine based on ctl-specific schizont... East coast fever vaccine based on ctl-specific schizont...

C - Chemistry, Metallurgy

07

K

C07K 14/44 (2006.01) A61K 39/018 (2006.01) C07K 16/20 (2006.01) C12N 15/10 (2006.01) C12N 15/30 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2537896

This invention relates to DNA, protein, and peptide compositions and methods for identification of intracellular antigens of pathogens, that stimulate animal cytotoxic lymphocytes in an antigen specific manner. Such antigens are prime candidates for the development of vaccines, useful for the prevention of intracellular pathogenic diseases such as East Coast Fever.

Cette invention concerne un ADN, une protéine et des compositions peptidiques ainsi que des procédés d'identification d'antigènes intracellulaires des pathogènes qui stimulent des lymphocytes cytotoxiques chez l'animal d'une façon spécifique aux antigènes. Ces antigènes sont les premiers candidats au développement de vaccins utiles dans la prévention de maladies pathogènes intracellulaires telles que la theilériose bovine.

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