Echinocandin/carbohydrate complexes

Details Echinocandin/carbohydrate complexes Echinocandin/carbohydrate complexes

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 47/48 (2006.01) C07K 9/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2362016

A complex of an echinocandin compound with a carbohydrate is described having improved thermal stability and water solubility. A process for making the echinocandin/carbohydrate complex is also described as well as the use of the complex in pharmaceutical formulations and treatments of fungal infections.

L'invention concerne un complexe de composé d'échinocandine, comprenant un lipide à stabilité thermique et solubilité dans l'eau améliorées. L'invention concerne également une technique de préparation du complexe d'échinocandine/lipide ainsi que l'utilisation dudit complexe dans des formulations pharmaceutiques et le traitement des infections fongiques.

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