C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2488413
Methods and kits for diagnosing and prognosticating cancer via detection of EEF1A2 and/or EEF1A2 are provided. Also provided are methods for treating cancer via inhibition of expression and/or activity of EEF1A2 and screening assays to identify new anticancer agents based upon their ability to inhibit EEF1A2 expression and/or activity. The methods and kits of the present invention are particularly useful in the prognosis, diagnosis and treatment of ovarian, breast and colorectal cancer.
L'invention concerne des méthodes et des nécessaires destinés au diagnostic et au pronostic du cancer, permettant de détecter <i>EEF1A2 </i> et/ou EEF1A2. L'invention concerne également des méthodes de traitement du cancer consistant à inhiber l'expression et/ou l'activité de EEF1A2, ainsi que des tests de criblage servant à identifier de nouveaux agents anticancéreux sur la base de leur faculté d'inhiber l'expression et/ou l'activité de EEF1A2. Les méthodes et les nécessaires de la présente invention sont particulièrement utiles pour le pronostic, le diagnostic et le traitement du cancer de l'ovaire, du cancer du sein et du cancer colorectal.
Cancer Care Ontario
Scribner Stephen J.
LandOfFree
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