Effect of n,n,n-trimethylsphingosine on protein kinase-c...

Details Effect of n,n,n-trimethylsphingosine on protein kinase-c... Effect of n,n,n-trimethylsphingosine on protein kinase-c...

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) A01N 1/02 (2006.01) A61K 31/13 (2006.01) A61K 35/14 (2006.01) C07C 215/40 (2006.01)

Patent

CA 2097324

2097324 9212119 PCTABS00014 The invention relates to a novel compound, compositions and medicaments thereof and a method of inhibiting cell proliferation, platelet aggregation (induced by various factors) and inhibiting malignant phenotypes of tumor cells such as those having a metastatic property, and modulating cell adhesion molecule expression and function using said compound, composition or medicament. N,N,N-trimethylsphingosine shows superior cell proliferation inhibitory and anti-metastatic activity over related compounds.

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