Effects of inhibitors of fgfr3 on gene transcription

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2630597

Methods of utilizing biomarkers to identify patients for treatment or to monitor response to treatment are taught herein. Alterations in levels of gene expression of the biomarkers, particularly in response to FGFR3 inhibition, are measured and identifications or adjustments may be made accordingly.

La présente invention concerne des procédés d'utilisation de biomarqueurs pour identifier des patients à traiter ou pour surveiller la réponse à un traitement. Des altérations des taux d'expression génétique des biomarqueurs, en particulier en réponse à l'inhibition de FGFR3, sont mesurées et des identifications ou ajustements peuvent être effectués en conséquence.

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