Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Details Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2582222

A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4- c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. Formula (I). These compounds can be useful as factor Xa inhibitors.

L'invention concerne un procédé d'élaboration et des intermédiaires pour l'élaboration de 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones, du type indiqué ci-après, en formule (I), à partir de phényl hydrazines appropriées. Ces composés peuvent être utiles comme inhibiteurs de facteur Xa.

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