Efficient transport into white blood cells

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/16 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2738989

The present invention relates to the use of specific transporter cargo conjugate molecules for the transport of a substance of interest (cargo molecule) into white blood cells. Said transporter cargo conjugate molecules may be used for the treatment, prophylaxis, attenuation and/or amelioration of a disease and/or disorder involving white blood cells. The present invention also relates to manufacture of said transporter cargo conjugate molecules, to a method of transporting a substance of interest (cargo) into a white blood cell and to a white blood cell comprising said transporter cargo conjugate molecules or fragments thereof.

La présente invention concerne l'utilisation de molécules conjuguées transporteuses/cargo spécifiques pour le transport d'une substance d'intérêt (molécule cargo) dans les globules blancs. Lesdites molécules conjuguées transporteuses/cargo peuvent être utilisées pour le traitement, la prophylaxie, l'atténuation et/ou l'amélioration d'une maladie et/ou d'un trouble impliquant les globules blancs. La présente invention concerne également la production desdites molécules conjuguées transporteuses/cargo, un procédé de transport d'une substance d'intérêt (cargo) dans un globule blanc et un globule blanc comprenant lesdites molécules conjuguées transporteuses/cargo ou un de leurs fragments.

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