Ehanced protein expression in bacillus

Details Ehanced protein expression in bacillus Ehanced protein expression in bacillus

C - Chemistry, Metallurgy

12

N

C12N 15/61 (2006.01) C07K 14/32 (2006.01) C12N 1/00 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/14 (2006.01) C12N 9/54 (2006.01) C12N 9/56 (2006.01) C12N 9/78 (2006.01) C12N 9/88 (2006.01) C12N 9/90 (2006.01) C12N 15/00 (2006.01) C12N 15/31 (2006.01) C12N 15/52 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12N 15/55 (2006.01) C12N 15/60 (2006.01) C12N 15/74 (2006.01) C12N 15/75 (2006.01) C12P 21/06 (2006.01)

Patent

CA 2480277

The present invention provides cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms, such as Bacillus species having enhanced expression of a protein of interest, wherein one or more chromosomal genes have been inactivated, and preferably wherein one or more chromosomal genes have been deleted from the Bacillus chromosome. In some further embodiments, one or more indigenous chromosomal regions have been deleted from a corresponding wild-type Bacillus host chromosome.

L'invention concerne des cellules ayant été génétiquement manipulées pour obtenir une capacité modifiée afin de produire des protéines exprimées. En particulier, l'invention concerne des micro-organismes gram-positifs, notamment l'espèceBacillus, présentant une expression améliorée d'une protéine à examiner, dans lesquels un ou plusieurs gènes chromosomaux ont été inactivés, et de préférence dans lesquels un ou plusieurs gènes chromosomaux ont été détruits à partir du chromosome de Bacillus. Dans d'autres modes de réalisation, une ou plusieurs zones chromosomales indigènes ont été effacées d'un chromosome hôte de Bacillus de type sauvage.

Affiliated with

Also associated with

Rating

Ehanced protein expression in bacillus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ehanced protein expression in bacillus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ehanced protein expression in bacillus will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1458173