Electrospun apatite/polymer nano-composite scaffolds

Details Electrospun apatite/polymer nano-composite scaffolds Electrospun apatite/polymer nano-composite scaffolds

C - Chemistry, Metallurgy

08

L

C08L 67/04 (2006.01) A61L 27/46 (2006.01) B32B 5/00 (2006.01) C08K 3/32 (2006.01) C08K 7/00 (2006.01) C08L 71/02 (2006.01)

Patent

CA 2680586

An artificial bone composite structure is provided. This structure includes a fibrous matrix that itself includes a plurality of fibers. Also, the structure includes a plurality of hydroxyapatite (HA) particles. These particles are dispersed within the fibrous matrix. Also, the HA particles have controlled size and aspect ratios and are aligned along long axes of the fibers. In some instances, the fibers include poly-(L-lactic acid) (PLLA).

Cette invention a trait à une structure composite osseuse artificielle. Cette structure comprend une matrice fibreuse qui comprend elle-même plusieurs fibres. La structure contient également plusieurs particules d'hydroxyapatite. Ces particules sont dispersées à l'intérieur de la matrice fibreuse. Les particules d'hydroxyapatite présentent également des rapports d'aspect et de taille contrôlés et s'alignent sur la longueur de l'axe des fibres. Dans certains cas, les fibres comprennent du poly(acide L-lactique)(PLLA).

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