Enantiomer (-) of tenatoprazole and the therapeutic use thereof

Details Enantiomer (-) of tenatoprazole and the therapeutic use thereof Enantiomer (-) of tenatoprazole and the therapeutic use thereof

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 1/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2509899

The invention relates to enantiomer (-) of tenatoprazole. The inventive enantiomer (-) of tenatoprazole, or (-)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]imidazo[4,5-b]pyridine exhibits improved pharmacocinetic properties which make it possible to use a once a day posology of a drug for relevant indications. Said invention can be used for curing digestive pathologies.

L'invention concerne l'EnantiomEre (-) du tEnatoprazole. L'EnatiomEre (-) du tEnatoprazole, ou (-)-5-mEthoxy-2-[[(4-mEthoxy-3,5-dimEthyl-2- pyridyl)mEthyl]sulfinyl]imidazo[4,5-b]pyridine, possEde des propriEtEs pharmacocinEtiques amEliorEes permettant une posologie d'une seule prise de mEdicament par jour dans les indications pertinentes. Application au traitement de pathologies digestives.

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