C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/20 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2578066
Enantiomerically pure compound of formula (I) are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
L'invention concerne un composé énantiomériquement pur représenté par la formule (I), (I) ainsi que des procédés de synthèse et des méthodes d'utilisation de ces composés. Les composés préférés sont des inhibiteurs puissants de la protéine kinase c-Met, et sont utiles pour le traitement des affections liées à une croissance cellulaire anormale telles que les cancers.
Cui Jingrong Jean
Funk Lee Andrew
Jia Lei
Kung Pei-Pei
Meng Jerry Jialun
Pfizer Inc.
Sim & Mcburney
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