A - Human Necessities – 23 – K
Patent
A - Human Necessities
23
K
A23K 1/16 (2006.01) A23K 1/00 (2006.01) A23K 1/18 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2110185
A composition of matter and method for administering a bioactive substance to the post-rumen portion of the digestive system of a ruminant substantially without introducing the substance to the rumen portion of the digestive system is provided. The composition of matter comprises particles which have a specific gravity between about 0.3 and 2.0, preferably between about 1.0 and 2Ø The particles comprise a core comprising bioactive substance; a hydrophobic coating essentially completely encapsulating said core in a quantity sufficient to essentially preclude introduction of bioactive substance into the rumen; and a surfactant applied to the surface of the hydrophobic coating in a quantity sufficient to ensure that said particles do not float on the rumen. The method comprises orally administering this composition to a ruminant.
Composition de matières et méthode pour administrer une substance bioactive dans la portion de l'appareil digestif d'un ruminant postérieure à la panse pratiquement sans introduire la substance en question dans la panse. La composition de matières est composée de particules ayant une densité située entre 0,3 et 2,0, de préférence entre environ 1,0 et 2,0. Ces particules consistent en un noyau comprenant une substance bioactive, en un revêtement hydrophobe encapsulant complètement le noyau en quantité suffisante pour empêcher essentiellement l'introduction de la substance bioactive dans la panse, et en un surfactant appliqué à la surface du revêtement hydrophobe en quantité suffisante pour faire en sorte que les particules en question ne flottent pas sur la panse. La méthode consiste à administrer la composition à un ruminant par voie orale.
Klose Robert E.
Balchem Corporation
Sim & Mcburney
LandOfFree
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