Epoxide hydrolases from streptomyces

Details Epoxide hydrolases from streptomyces Epoxide hydrolases from streptomyces

C - Chemistry, Metallurgy

12

N

C12N 9/14 (2006.01) C12N 15/31 (2006.01) C12P 7/02 (2006.01) C12P 41/00 (2006.01) C12Q 1/34 (2006.01)

Patent

CA 2380185

The invention relates to epoxide hydrolases from bacteria of the genus Streptomyces sp., to a novel method for the enzymatic separation of epoxide-enantiomer mixtures, to a novel assay method for epoxide hydrolase activity, to a screening method for detecting epoxide hydrolase activity and to the use of bacteria of the genus Streptomyces sp. and the epoxide hydrolases obtained from them for an enantio-selective epoxide hydrolysis.

La présente invention concerne des époxyde-hydrolases provenant de bactéries de l'espèce des Streptomyces, un procédé de séparation enzymatique de mélanges époxyde-énantiomère, un procédé d'identification de l'activité des époxyde-hydrolases, un procédé de visualisation servant à l'identification de l'activité des époxyde-hydrolases, et l'utilisation de bactéries de l'espèce des Streptomyces ainsi que les époxyde-hydrolases ainsi obtenues, servant à l'hydrolyse époxyde énantiosélective.

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