Essentially pure acid hydroxyl ligand aluminum complexes and...

Details Essentially pure acid hydroxyl ligand aluminum complexes and... Essentially pure acid hydroxyl ligand aluminum complexes and...

C - Chemistry, Metallurgy

07

F

167/123, 260/323

C07F 5/06 (2006.01) A61K 31/28 (2006.01)

Patent

CA 1273944

ABSTRACT Essentially pure acid hydroxyl ligand aluminum complexes useful as antacids are prepared by first reacting an acid hydroxyl ligand with an aluminum alkoxide under anhydrous conditions to form an intermediate and further reacting the intermediate with water, these complexes are useful as antacids and as such in the treatment of hyperacidity, and have the general formula: Al(L)x(OH)y, wherein x = 0.5, 1, y = 2 and L is an acid hyroxyl ligand selected from the group consisting of serine, homoserine, threonine, tyrosine, hydroxyproline, bicine, tricine and hydroxylysine when x = 1 and pamoic acid when x = 0.5.

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